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Great Dane Puppies for Sale in Florida by Uptown Puppies

Find the Perfect Great Dane

Browse Great Dane puppies for sale from 5 Star Breeders with Uptown Puppies.

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Great Dane Puppies for Sale in Florida by Uptown Puppies

About Great Danes

Both the biggest living dog and the biggest dog EVER are Great Danes. These gentle giants are incredibly sweet with children (but they might scare away a few strangers with their bark). Some families consider the Great Dane to be the ultimate family pet, period.

Size 10/10
Intelligence 7/10
Good with kids 9/10
Playfulness 7/10
Trainability 8/10
Grooming Ease 8/10
Energy Level 7/10
Stranger Friendly 9/10

Loyal and Loving

Great Danes are famous for their loving, loyal personalities—just ask Shaggy what he thought of Scooby Doo.

Gentle and Kind

Despite their size, Great Danes are fantastically friendly and get along with people of all ages—even strangers.

Jumbo Sized

The Great Dane’s size is part of its appeal. There’s just something endearing about that big ol’ face greeting you every morning!

Easy to Groom

Great Danes are a cinch to groom, despite their tendency to shed. If you’re busy and don’t have time for constant brushing, this is the dog for you!

Easy to Train

Great Danes are avid students and always love to please their owner with new tricks (as long as you have plenty of yummy treats).

Fun for the Whole Family

Great Danes are incredible, friendly family dogs that make fast friends with children and adults alike.

great dane puppies for sale

Our 3 Part Mission

The happiness of our customers, our breeders, and your puppy is the foundation of everything we do.


Connect responsible, ethical breeders with responsible, ethical buyers. Our mission is to take the uncertainty and headache out of finding the perfect puppy.


Help owners keep their puppies happy and healthy throughout the dog's entire life by sourcing and creating the best products, services, and learning materials.


Accelerate the elimination of puppy mills by empowering humane breeders and exposing those with inhumane operations. We want to be part of the solution.

5 star puppy finder

5 Star Breeders

We only work with Great Dane breeders who pass our 47 breeder standards. Here are a few of them...

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Vintage Pups

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Puppy Place

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale


5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Ralphs Puppies

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale


5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale


5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Top Line Pups

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Prestigious Pups

5 Star Breeder

About Uptown Approved Breeders

No puppy mills. No scams. We thoroughly vet all breeders based on our 47 Breeder Standards. When you find a puppy at Uptown, you're not just getting a dog--you're getting peace of mind that your new best friend is coming from an experienced, ethical breeder who loves dogs just as much as you do.

See the 47 Standards

Puppy Finder by Uptown Puppies

Questions & Answers

Questions about Great Dane puppies for sale in Florida? We have answers.

How much are Great Dane puppies for sale in Florida?

The truth is that every dog is different, and this goes for every Great Dane for sale Florida too. They all have their preferences and characters. Some will eat anything you put in front of them, while others will be a little pickier. We don't recommend any specific food in particular for a Great Dane for sale in Florida, but we do encourage you to try different things, read reviews, and consult your vet.

What is the difference between a purebred dog and a mixed breed dog?

A Great Dane Florida is an example of a purebred dog, which is one that has been bred for specific standards, with two parents of the same established breed. A mixed-breed dog, meanwhile, is one that has different breed parents or ancestry where different breeds were crossed together.

What if I want a specific kind of Great Dane?

You'll find Florida Great Dane breeders offering a lot of different options here on Uptown. From harlequin Florida Great Dane puppies for sale to many other colors and types, there's plenty to choose from, and one of the most fun parts of picking a Great Dane is having all of those different options where every pup feels totally unique.

What should I expect if I get a Great Dane?

First off, these are big dogs, so you need to be ready to welcome a sizable animal into your home. Great Dane puppies for sale in Florida might not seem all that huge at first, but they grow quickly and can reach heights of 30” with ease. The tallest Great Danes even go past the 40” mark! In terms of temperament, each dog is different, but this breed is known for being gentle, intelligent, and loyal.

How can I be sure that my Great Dane puppy will be healthy?

When you buy a Florida Great Dane puppy for sale on Uptown, you get a guaranteed nose-to-tail health check, offered by the breeder. This health check will give you a full overview of your pup's health, reporting on any possible issues, diseases, or disorders. This way, you'll be able to get the all-clear before bringing your new furry friend home.

How much exercise do these dogs need?

Great Danes for sale Florida are big dogs with long, muscular legs and a lot of energy to burn. They'll need at least an hour of exercise each day and appreciate long walks. They like getting into nature too and sniffing around new places, so will be happy to explore different areas instead of always going around the same neighborhood.

Are there any health issues that can affect this breed?

On average, Great Dane puppies Florida will live to an age of around 8-10. Unfortunately, they don't have the same long lifespans as other breeds, and they are at risk of certain severe health issues such as heart disease, thyroid issues, and bloat, which can all be fatal in certain cases. To have the best chance of finding a healthy pup with a long life expectancy, always buy from vetted Great Dane breeders in Florida.

How do I use Uptown to find my Great Dane pup?

There are many sites out there that offer to help you find Great Dane puppies for sale Florida, but Uptown aims to keep the process as simple and straightforward as possible, putting you in direct contact with vetted, trusted breeders from around the US. Check out the available Florida Great Danes for sale to get started and speak with the sellers to learn more about the pups that pique your interest.

Do you sell the cheapest Great Danes on Uptown?

Price is always a big concern when looking for a new dog, but we recommend that you don't focus purely and simply on finding the cheapest Great Danes for sale in Florida. Why? Well, super cheap dogs are often sold by scammers and puppy mills, meaning that they have a high risk of health problems that could cost you so much more money to fix through veterinary care.

Why shouldn’t I opt for a shelter dog instead of a breeder dog?

As dog lovers, we respect and admire the wonderful work done by shelters, and a shelter could be right for you, so we encourage everyone to think carefully before deciding on their next canine companion. If you don't mind too much about specific pedigrees and health histories, shelter dogs might be fine, but if you want something specific, like a Florida Great Dane for sale, and want to have a full health history, Uptown is the better choice.

Great Dane Puppies for Sale by Uptown Puppies

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