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Home Breeds Great Dane San Francisco CA

Great Dane Puppies for Sale in San Francisco CA by Uptown Puppies

Find the Perfect Great Dane

Browse Great Dane puppies for sale from 5 Star Breeders with Uptown Puppies.

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Great Dane Puppies for Sale in San Francisco CA by Uptown Puppies

About Great Danes

Both the biggest living dog and the biggest dog EVER are Great Danes. These gentle giants are incredibly sweet with children (but they might scare away a few strangers with their bark). Some families consider the Great Dane to be the ultimate family pet, period.

Size 10/10
Intelligence 7/10
Good with kids 9/10
Playfulness 7/10
Trainability 8/10
Grooming Ease 8/10
Energy Level 7/10
Stranger Friendly 9/10

Loyal and Loving

Great Danes are famous for their loving, loyal personalities—just ask Shaggy what he thought of Scooby Doo.

Gentle and Kind

Despite their size, Great Danes are fantastically friendly and get along with people of all ages—even strangers.

Jumbo Sized

The Great Dane’s size is part of its appeal. There’s just something endearing about that big ol’ face greeting you every morning!

Easy to Groom

Great Danes are a cinch to groom, despite their tendency to shed. If you’re busy and don’t have time for constant brushing, this is the dog for you!

Easy to Train

Great Danes are avid students and always love to please their owner with new tricks (as long as you have plenty of yummy treats).

Fun for the Whole Family

Great Danes are incredible, friendly family dogs that make fast friends with children and adults alike.

great dane puppies for sale

Our 3 Part Mission

The happiness of our customers, our breeders, and your puppy is the foundation of everything we do.

Connect...

Connect responsible, ethical breeders with responsible, ethical buyers. Our mission is to take the uncertainty and headache out of finding the perfect puppy.

Educate...

Help owners keep their puppies happy and healthy throughout the dog's entire life by sourcing and creating the best products, services, and learning materials.

Accelerate...

Accelerate the elimination of puppy mills by empowering humane breeders and exposing those with inhumane operations. We want to be part of the solution.

5 star puppy finder

5 Star Breeders

We only work with Great Dane breeders who pass our 47 breeder standards. Here are a few of them...

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Vintage Pups

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Puppy Place

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

PuppySpot

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Ralphs Puppies

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

BigBoys

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

PuppyTime

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Top Line Pups

5 Star Breeder

Uptown Puppies Great Dane Breeder
Great Dane Puppies for Sale

Prestigious Pups

5 Star Breeder

About Uptown Approved Breeders

No puppy mills. No scams. We thoroughly vet all breeders based on our 47 Breeder Standards. When you find a puppy at Uptown, you're not just getting a dog--you're getting peace of mind that your new best friend is coming from an experienced, ethical breeder who loves dogs just as much as you do.

See the 47 Standards

Puppy Finder by Uptown Puppies

Questions & Answers

Questions about Great Dane puppies for sale in San Francisco CA? We have answers.

How much are Great Dane puppies for sale in San Francisco CA?

Searching for a specific variety of San Francisco Great Dane puppies for sale? That's no problem! One of the fun things about this breed is that they can be found in so many different colors. You'll discover plenty of options on Uptown with featured San Francisco Great Dane breeders and other sellers all over the US.

Where did the Great Dane breed originate?

Finding a Great Dane San Francisco isn't difficult these days and the breed is beloved all over the world, but back in the past, these dogs could only be found in Germany. They descended from large English hunting breeds and were first used for hunting wild boar in the woods. As time went by, they became much more docile, making them fine family pets.

What should I expect from a Great Dane?

All Great Dane puppies for sale in San Francisco have their own qualities and characteristics to discover, but one thing you can always be sure of with this breed is that they'll grow to quite a size! Great Danes can tip the scales at close to 180 lbs and often measure close to 30” in height, so they're not the best option for those in little homes.

How do I know that my Great Dane puppy will be healthy?

The breeders and businesses featured on Uptown will always offer nose-to-tail health checks on every San Francisco Great Dane puppy for sale. These checks are very detailed and in-depth, covering everything from the eyes and ears to the internal organs and more. Thanks to this, you'll know all the details on your pup's health before you even bring it home.

Is it enough to walk my Great Dane, or do they need more exercise?

Anyone wanting to adopt Great Danes for sale San Francisco needs to be aware that these dogs need real exercise. A simple stroll around the block won't be enough; Great Danes are big, muscular dogs that require a long, daily work of up to an hour. They'll also benefit from having a big backyard or outdoor space to run around in.

What kinds of health issues can affect this breed?

Great Dane puppies San Francisco can live for about 8-10 years on average, but their lives can be cut short by certain health issues. These dogs can struggle with bone and joint issues such as hip and elbow dysplasia. Heart problems and bloat are other problems to look out for. Be sure to buy from trusted Great Dane breeders in San Francisco to have the best chance of a happy pup with a long life expectancy.

How do I use Uptown for finding Great Dane puppies?

If you're ready to start searching for San Francisco Great Danes for sale, the process really couldn't be any easier. The Uptown network is filled with vetted breeders and trusted sellers of Great Dane puppies for sale San Francisco, and you can browse through all the pups that are for sale right now in search of your dream dog. Once you find one you like, chat with the breeder to proceed.

What's Uptown's opinion on transparency when it comes to breeding puppies?

At Uptown, we feel that transparency is a vital part of buying a puppy. When looking for a new dog, like a Great Dane for sale San Francisco, you need to know that you're buying from someone you can trust. That's why we take the time to vet every breeder and business, only approving those who are open and honest with their customers. So when you use Uptown to find a Great Dane for sale in San Francisco, you won't need to worry about transparency.

Do you sell the cheapest Great Danes here?

Everyone should have a budget in mind when shopping for dogs like Great Danes for sale in San Francisco, but looking for the 'cheapest' pups might be dangerous. Often, the lowest priced dogs may secretly have health or behavioral issues or could be sold by scammers. At Uptown, you'll find pups with competitive prices, raised the right way by honest, ethical sellers.

Why shouldn’t I choose a shelter dog instead of a breeder dog?

We absolutely support the inspiring work being done by shelters and rescue centers across America, and it's always important to take your time and consider your options when thinking about a new dog. A shelter might not be the right choice for you if you want a specific breed in particular, like a San Francisco Great Dane for sale, as you can't always predict what breeds will end up in local shelters.

Great Dane Puppies for Sale by Uptown Puppies

Puppies available!

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